Abstract

Objectives: If approved for use in young males in the United States, prophylactic HPV vaccine may reduce the incidence of HPV-related disease in vaccinated males and their sexual partners. We aimed to characterize heterosexual males’ willingness to get HPV vaccine and identify correlates of vaccine acceptability.

Methods: Participants were from a national sample of heterosexual men (n=297) aged 18 to 59 from the United States who were interviewed in January 2009. We analyzed data using multivariate logistic regression.

Results: Most men had not heard of HPV prior to the study or had low HPV knowledge (81%, 239/296). Most men had heard of HPV vaccine prior to the study (63%, 186/296), and 37% (109/296) were willing to get HPV vaccine. Men were more willing to get vaccinated if they reported higher perceived likelihood of getting HPV-related disease (OR=1.80, 95% CI: 1.02–3.17), perceived HPV vaccine effectiveness (OR=1.86, 95% CI: 1.22–2.83), or anticipated regret if they did not get vaccinated and an HPV infection later developed (OR=2.01, 95% CI: 1.40–2.89). Acceptability was also higher among men who thought (OR=9.02, 95% CI: 3.45–23.60) or were unsure (OR=2.67, 95% CI: 1.30–5.47) if their doctor would recommend they get HPV vaccine, if licensed for males.

Conclusions: Men had low HPV knowledge and were moderately willing to get HPV vaccine. These findings underscore the need for HPV educational efforts for men and provide insight into some of the factors that may affect the HPV vaccination decision making process among men.