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A clinical trial (ANRS IPERGAY) among 232 men who have sex with men (MSM) using HIV pre-exposure prophylaxis (HIV-PrEP) showed efficacy of postexposure prophylaxis with doxycycline in reducing chlamydia and syphilis.1 A survey showed high interest (84%) in trying doxycycline prophylaxis for prevention of STIs among MSM in the USA.2 Actual use has been estimated to be nearly 10% among MSM using HIV-PrEP in the UK3 and Australia.4 However, the use of doxycycline STI-prophylaxis is not recommended in UK guidelines because of risk for selection and dissemination of doxycycline-resistant strains.5 In the Netherlands and most European countries, doxycycline STI-prophylaxis is not prescribed by sexual health clinics and general practitioners. This study is the first estimate of STI-prophylaxis use among MSM in the Netherlands.
The …