Footnotes

• Handling editor Jason J Ong

• Twitter @giumas3

• Contributors MG and AL conceived the idea for the report; MG and MGD performed the data collection and interpreted the results; MG, AL and MGD prepared the manuscript for publication; AL, AC and MG consulted the patients and collected clinical data; FP performed the serological tests; ALM and MSP conceived and cured the drug delivery from the hospital pharmacy. All authors have read and approved the final version of the manuscript.

• Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

• Competing interests None declared.

• Provenance and peer review Not commissioned; externally peer reviewed.