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Several SARS-CoV-2 vaccines are being rolled out worldwide, following testing in healthy volunteers and smaller groups of people with comorbidities, including HIV.1 Human T-cell leukaemia virus type 1 (HTLV-1), a retrovirus like HIV, is oncogenic and can cause chronic immune dysfunction. However, there is no established antiretroviral treatment for HTLV-1. An estimated 10 million individuals live with HTLV-1 worldwide. Two main disease patterns are recognised: lymphoproliferative immunodeficient (adult T-cell leukaemia/lymphoma) and inflammatory immunodysfunctional (HTLV-1-associated myelopathy).
HTLV-1 is an under-researched virus, only recently adopted …
Footnotes
Handling editor Anna Maria Geretti
Contributors AA conceived the idea of this project and coauthored the manuscript. FM reviewed and coauthored the manuscript.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.