RT Journal Article SR Electronic T1 A new look at the serology of treponemal disease. JF The British Journal of Venereal Diseases JO Br J Vener Dis FD BMJ Publishing Group Ltd SP 296 OP 299 DO 10.1136/sti.52.5.296 VO 52 IS 5 A1 O'Neill, P YR 1976 UL http://sti.bmj.com/content/52/5/296.abstract AB The serology of treponemal disease has become simpler and more rational in recent years, mainly as a result of the widespread adoption of specific antibody tests and the use of monospecific fluorescent antibody procedures which give information about the immunoglobulin class of antibodies. A set of tests which has proved particularly useful in routine diagnosis is the following: quantitative TPHA test, quantitative VDRL test, and monospecific (IgG and IgM) FTA-ABS tests. This combination is especially valuable in the assessment of new patients with positive results to serological tests and in the management of patients with treated syphilis.