PT  - JOURNAL ARTICLE
AU  - D A Street
AU  - D Taylor-Robinson
AU  - C M Hetherington
TI  - Infection of female squirrel monkeys (Saimiri sciureus) with trichomonas vaginalis as a model of trichomoniasis in women.
AID  - 10.1136/sti.59.4.249
DP  - 1983 Aug 01
TA  - The British Journal of Venereal Diseases
PG  - 249--254
VI  - 59
IP  - 4
4099  - http://sti.bmj.com/content/59/4/249.short
4100  - http://sti.bmj.com/content/59/4/249.full
SO  - Br J Vener Dis1983 Aug 01; 59
AB  - Marmosets, tamarins, owl monkeys, and squirrel monkeys were inoculated intravaginally with Trichomonas vaginalis. The latter animal species was most susceptible, trichomonads being recovered from four of six monkeys for periods ranging usually up to one month. Vaginal discharge was seen in most infected animals but polymorphonuclear leucocytes were rare. Infected animals developed serum IgG antibody responses and also local IgG and IgA responses, the latter occurring sometimes on reinoculation in the absence of organism recovery. Antibody responses were, however, of short duration and, overall, immunity was weak because two animals were reinfected on a second or subsequent challenge. Some of the observations are relevant to vaginal trichomoniasis in women.