RT Journal Article SR Electronic T1 Treponema-specific and antilipoidal 19S(IgM) antibodies in penicillin-treated and untreated rabbits after infection with Treponema pallidum. JF The British Journal of Venereal Diseases JO Br J Vener Dis FD BMJ Publishing Group Ltd SP 15 OP 19 DO 10.1136/sti.57.1.15 VO 57 IS 1 A1 Müller, F A1 Oelerich, S YR 1981 UL http://sti.bmj.com/content/57/1/15.abstract AB The titres of treponema-specific and antilipoidal 19S(IgG) antibodies were determined in rabbits infected intratesticularly with Treponema pallidum. One group of rabbits was treated with penicillin the other served as control. Using different serological tests it was shown that 19S(IgM) antibodies were still detectable eight months after infection at about the same titres in both groups. In contrast, 19S(IgM) antibody titres in patients with syphilis became undetectable within three to six months after penicillin treatment. It is suggested therefore that the rabbit is not a reliable model for studying the effect of penicillin in human T pallidum infections.