TY - JOUR T1 - Activity of ciprofloxacin against genital tract pathogens. JF - The British Journal of Venereal Diseases JO - Br J Vener Dis SP - 316 LP - 318 DO - 10.1136/sti.60.5.316 VL - 60 IS - 5 AU - C A Hart AU - S J How AU - D Hobson Y1 - 1984/10/01 UR - http://sti.bmj.com/content/60/5/316.abstract N2 - The in vitro activity of the quinolone carboxylic acid, ciprofloxacin, against a variety of genital tract pathogens was examined. Each of 35 isolates of Neisseria gonorrhoeae, including some beta-lactamase producing strains and strains resistant to tetracycline, was inhibited at a concentration of 0.01 mg/l. Most (13 of 20) strains of Gardnerella vaginalis were inhibited at 1 mg/l but three isolates had minimum inhibitory concentrations (MICs) of 8 mg/l or more. Each of seven strains of Chlamydia trachomatis was completely inhibited at a concentration of 2 mg/l. Prolonged (72 hours) exposure of the chlamydiae to ciprofloxacin was required for inhibition at this concentration. ER -