PT  - JOURNAL ARTICLE
AU  - C A Hart
AU  - S J How
AU  - D Hobson
TI  - Activity of ciprofloxacin against genital tract pathogens.
AID  - 10.1136/sti.60.5.316
DP  - 1984 Oct 01
TA  - The British Journal of Venereal Diseases
PG  - 316--318
VI  - 60
IP  - 5
4099  - http://sti.bmj.com/content/60/5/316.short
4100  - http://sti.bmj.com/content/60/5/316.full
SO  - Br J Vener Dis1984 Oct 01; 60
AB  - The in vitro activity of the quinolone carboxylic acid, ciprofloxacin, against a variety of genital tract pathogens was examined. Each of 35 isolates of Neisseria gonorrhoeae, including some beta-lactamase producing strains and strains resistant to tetracycline, was inhibited at a concentration of 0.01 mg/l. Most (13 of 20) strains of Gardnerella vaginalis were inhibited at 1 mg/l but three isolates had minimum inhibitory concentrations (MICs) of 8 mg/l or more. Each of seven strains of Chlamydia trachomatis was completely inhibited at a concentration of 2 mg/l. Prolonged (72 hours) exposure of the chlamydiae to ciprofloxacin was required for inhibition at this concentration.