PT  - JOURNAL ARTICLE
AU  - M J van de Laar
AU  - Y T van Duynhoven
AU  - J S Fennema
AU  - J M Ossewaarde
AU  - A J van den Brule
AU  - G J van Doornum
AU  - R A Coutinho
AU  - J A van den Hoek
TI  - Differences in clinical manifestations of genital chlamydial infections related to serovars.
AID  - 10.1136/sti.72.4.261
DP  - 1996 Aug 01
TA  - Genitourinary Medicine
PG  - 261--265
VI  - 72
IP  - 4
4099  - http://sti.bmj.com/content/72/4/261.short
4100  - http://sti.bmj.com/content/72/4/261.full
SO  - Genitourin Med1996 Aug 01; 72
AB  - OBJECTIVES: To study the association of serovars of Chlamydia trachomatis with clinical manifestations of genital tract infection and socio-demographic characteristics. METHODS: In 1986-88 the C trachomatis isolates from 159 heterosexual men and 116 women attending a sexually transmitted disease (STD) clinic were collected and typed accordingly. A medical history was recorded, a physical examination took place and samples were taken for laboratory diagnostics. RESULTS: Serovars E, F and D were the most common for both men (75%) and women (67%). Men infected with serovars of the C-complex had more often a history of STD (p = 0.06). The opposite was demonstrated in women (p = 0.07). In addition, women younger than 18 years at first intercourse were more often infected with C-complex serovars (p = 0.05). For men, the serovars F/G less often produced symptoms of urethral discharge (p = 0.01) than the serovars of the B-complex and C-complex and were less often associated with the presence of 10 or more leukocytes in a Gram-stained smear (p = 0.04). CONCLUSIONS: In this study, infections with serovars F and G caused less obvious symptoms and signs of inflammation in men; in women no differences were found in the clinical manifestation of infections with different serovars.