PT - JOURNAL ARTICLE AU - B Vuylsteke AU - M Vandenbruaene AU - P Vandenbalcke AU - E Van Dyck AU - M Laga TI - Chlamydia trachomatis prevalence and sexual behaviour among female adolescents in Belgium. AID - 10.1136/sti.75.3.152 DP - 1999 Jun 01 TA - Sexually Transmitted Infections PG - 152--155 VI - 75 IP - 3 4099 - http://sti.bmj.com/content/75/3/152.short 4100 - http://sti.bmj.com/content/75/3/152.full SO - Sex Transm Infect1999 Jun 01; 75 AB - OBJECTIVES: To determine prevalence and risk factors of Chlamydia trachomatis among female secondary school students and to develop potential selective screening strategies. METHODS: A cross sectional survey was conducted in the 17 school medical centres in Antwerp municipality, Belgium. All female students of forms 5 or 6, who were due for their medical check up during the school year 1996-7, were invited to participate. A self administered questionnaire on general and sexual behaviour, and a first void urine sample were collected. The urine specimen was tested for C trachomatis with ligase chain reaction assay, and positive tests were confirmed with polymerase chain reaction assays. RESULTS: 2784 female students participated in the study. Their median age was 17, and 52% of them reported having sexual intercourse at least once. The prevalence of C trachomatis among sexually active women was 1.4%. Factors significantly associated with infection in multivariate analysis were number of lifetime partners, genital complaints of partner, type of secondary school, and a history of pregnancy. Selective screening of those women who are at highest risk for infection would have detected 90% of all infections, and require testing of 14% to 18% of the population. CONCLUSIONS: The prevalence of C trachomatis was relatively low among female secondary school students in Antwerp, but unsafe sex practices were evident because of the high number of unplanned pregnancies. Selective screening strategies with a high sensitivity can be proposed, but should be assessed for acceptability, feasibility, and cost.