TY - JOUR T1 - Doxycycline failure in lymphogranuloma venereum JF - Sexually Transmitted Infections JO - Sex Transm Infect SP - 278 LP - 279 DO - 10.1136/sti.2009.042093 VL - 86 IS - 4 AU - Frédéric Méchaï AU - Bertille de Barbeyrac AU - Olivier Aoun AU - Audrey Mérens AU - Patrick Imbert AU - Christophe Rapp Y1 - 2010/08/01 UR - http://sti.bmj.com/content/86/4/278.abstract N2 - Lymphogranuloma venereum (LGV) cases are currently re-emerging in the homosexual community, particularly in HIV-seropositive patients. The standard treatment for this infection, which is caused by Chlamydia trachomatis L1, L2 and L3 serotypes, is a 3-week doxycycline regimen. The case is reported of a male patient presenting with LGV, who was rapidly cured with moxifloxacin treatment after failure of extended treatment with cyclines. This fluoroquinolone is known to be highly active in vitro on the LGV pathogenic agent. Thus it may be a useful alternative when doxycycline treatment results in failure. ER -