RT Journal Article
SR Electronic
T1 P3-S7.11 Factors associated with persistent Bacterial Vaginosis among young reproductive age women in Mysore, India
JF Sexually Transmitted Infections
JO Sex Transm Infect
FD BMJ Publishing Group Ltd
SP A302
OP A303
DO 10.1136/sextrans-2011-050108.494
VO 87
IS Suppl 1
A1 P Madhivanan
A1 S Rathod
A1 K Krupp
A1 A Arun
A1 A Reingold
A1 C Cohen
A1 J Klausner
YR 2011
UL http://sti.bmj.com/content/87/Suppl_1/A302.3.abstract
AB Background Bacterial vaginosis (BV) is a common infection and has been associated with adverse health outcomes including preterm birth, pelvic inflammatory disease and acquisition of HIV and other sexually transmitted diseases. There are limited data on persistent BV in Indian women. This study examined the risk factors for persistent bacterial vaginosis in young reproductive women in India. Study Design Between November 2005 and January 2007, a prospective cohort study was carried out to examine the relationship of BV and HSV-2 acquisition among women in Mysore. Quarterly, data were collected on sociodemographics, risk behaviour, partner characteristics, followed by a physical examination to diagnose and treat reproductive tract infections. BV was defined using Nugent scoring of gram stained vaginal smears. Persistent BV was calculated using generalised estimating equation methods. Women gave informed consent prior to enrolment in the study. Results Of the 420 women for which there were data available for all three visits, 114 (27%) had two or more BV episodes. Women with a history of 2 or more BV episodes were more likely to be infected with Trichomonas vaginalis [OR 72.93, 95% CI 9.69 to 548.4] and be diagnosed with HSV-2 infection [OR 2.58, 95% CI 1.44 to 4.63] compared to women with no BV history. Women with a history of BV were also more likely to report no education, tubal ligation, being a non-Muslim, and having a sex partner who had other sex partners. Conclusions Young reproductive age women in India have a high persistence of BV. Although the association between BV and Trichomonas vaginalis is unclear, it seems prudent to recommend that women with BV or TV be screened for both infections.