PT  - JOURNAL ARTICLE
AU  - Gundevia, Zarin
AU  - Foster, Rosalind
AU  - Jamil, Muhammad Shahid
AU  - McNulty, Anna
TI  - Positivity at test of cure following first-line treatment for genital <em>Mycoplasma genitalium</em>: follow-up of a clinical cohort
AID  - 10.1136/sextrans-2014-051616
DP  - 2015 Feb 01
TA  - Sexually Transmitted Infections
PG  - 11--13
VI  - 91
IP  - 1
4099  - http://sti.bmj.com/content/91/1/11.short
4100  - http://sti.bmj.com/content/91/1/11.full
SO  - Sex Transm Infect2015 Feb 01; 91
AB  - Objectives To describe antibiotic use for treatment of Mycoplasma genitalium (MG) at an urban sexual health centre in Australia. To describe MG positivity rates in those returning for 1 month test of cure (TOC) following first-line antibiotic treatment for MG. Methods Retrospective cross-sectional case-note review for all patients diagnosed with MG at Sydney Sexual Health Centre from 2009 to 2013. Results Two hundred and eighteen MG cases were identified; 66% were male and 90% were symptomatic at presentation. Four people did not return for treatment. Azithromycin containing regimens were prescribed as first-line treatment in 88% of cases; azithromycin 1 g stat in 75% of cases and a course of extended azithromycin 1 g stat plus 500 mg daily for 4 days in 14% of cases. TOC was performed in 53% (95% CI 46% to 60%) of cases and 28% (95% CI 20% to 38%) of these cases were MG-positive at TOC. Of those having a MG-positive result at TOC, 26% received azithromycin 1 g stat and 33% received extended azithromycin. Accounting for cases lost to follow-up in azithromycin containing regimens, the positive MG TOC rate was estimated to be between 15% and 61%. Conclusions High rates of MG positivity were found in those attending TOC following first-line treatment of MG with azithromycin containing regimens.