RT Journal Article SR Electronic T1 Prevalence and correlates of oral human papillomavirus infection among healthy males and females in Lima, Peru JF Sexually Transmitted Infections JO Sex Transm Infect FD BMJ Publishing Group Ltd SP 149 OP 154 DO 10.1136/sextrans-2014-051942 VO 92 IS 2 A1 Brian J Rosen A1 Leora Walter A1 Robert H Gilman A1 Lilia Cabrerra A1 Patti E Gravitt A1 Morgan A Marks YR 2016 UL http://sti.bmj.com/content/92/2/149.abstract AB Purpose The incidence of human papillomavirus (HPV) associated head and neck cancers (HNCs) have been increasing in Peru. However, the burden of oral HPV infection in Peru has not been assessed. The objective of this cross-sectional study was to estimate the prevalence and correlates of oral HPV infection in a population-based sample from males and females from Lima, Peru.Methods Between January 2010 and June 2011, a population-based sample of 1099 individuals between the ages of 10 and 85 from a low-income neighbourhood in Lima, Peru was identified through random household sampling. Information on demographic, sexual behaviours, reproductive factors and oral hygiene were collected using interviewer-administered questionnaires. Oral rinse specimens were collected from each participant, and these specimens were genotyped using the Roche Linear Array assay. ORs were used to assess differences in the prevalence of any oral HPV and any high-risk oral HPV infection by demographic factors, sexual practices and oral hygiene among individuals 15+ years of age.Results The prevalence of any HPV and any high-risk HPV (HR-HPV) was 6.8% and 2.0%, respectively. The three most common types were HPV 55 (3.4%), HPV 6 (1.5%) and HPV 16 (1.1%). Male sex (aOR, 2.21; 95% CI 1.22 to 4.03) was associated with any HPV infection after adjustment.Conclusions The prevalence of oral HPV in this study was similar to estimates observed in the USA. Higher prevalence of oral infections in males was consistent with a male predominance of HPV-associated HNCs and may signal a sex-specific aetiology in the natural history of infection.