RT Journal Article SR Electronic T1 P170 Risk factors for Mycoplasma genitalium infection in symptomatic males, females and men who have sex with men from three clinical settings in London JF Sexually Transmitted Infections JO Sex Transm Infect FD BMJ Publishing Group Ltd SP A77 OP A77 DO 10.1136/sextrans-2016-052718.220 VO 92 IS Suppl 1 A1 Claire Broad A1 Emma Harding-Esch A1 Mark Harrison A1 Clare Soares A1 Sebastian Fuller A1 Sandra Okala A1 John Saunders A1 Tristan Barber A1 Phillip Hay A1 Tariq Sadiq YR 2016 UL http://sti.bmj.com/content/92/Suppl_1/A77.1.abstract AB Background/introduction Mycoplasma genitalium (MG), a sexually transmitted infection (STI), is increasingly recognised as a cause of major reproductive health sequelae. Treatment has become increasingly difficult due to macrolide and fluoroquinolone antibiotic resistance. MG is not routinely tested for in most UK genitourinary medicine (GUM) clinics, and limited risk-factor data exist for infection in at-risk populations and in different anatomical sites.Aim(s)/objectives To determine risk factors for MG infection in symptomatic male and female patients accessing three London GUM clinics.Methods Patients aged ≥16 years, symptomatic of an STI (or Chlamydia, Gonorrhoea, Trichomonas vaginalis, or non-specific urethritis contact) were consented. Additional-to-routine samples provided were vulvovaginal swab (VVS) (females), first void urine (FVU) (men-who-have-sex-with-women (MSW), (men-who-have-sex-with-men (MSM)), pharyngeal and rectal swabs (MSM). Samples were tested using the FTD Urethritis Plus Test kit and positives confirmed by Polymerase Chain Reaction. Risk factors were analysed using univariate and multivariate logistic regression.Results MG was detected in: 10.7% (95% CI 7.9%–13.5%) patients; 7.9% (95% CI 4.86%–10.94%) VVS; 19.4% (95% CI 11.76%–27.04%) MSW urine; 1.6% (95% CI 0%–4.72%) MSM urine; 0% MSM pharynx; 8.1% (95% CI 1.31%–14.89%) MSM rectum.View this table:Abstract P170 Table 1 Risk factors associated with MG infectionDiscussion/conclusion MG positivity was highest in MSW compared to the other patient groups, with younger age being the only risk factor for infection, remaining after multivariate analysis. The presence of rectal MG despite a lack of urogenital infection in MSMs warrants further investigation with a larger cohort. Overall the results indicate high MG positivity across symptomatic male and female populations.