PT - JOURNAL ARTICLE AU - Benjamin Bavinton AU - Stefanie Vaccher AU - Martin Holt AU - Rebecca Guy AU - Garrett Prestage AU - Fengyi Jin AU - Janaki Amin AU - David Templeton AU - Christine Selvey AU - Iryna Zablotska-Manos AU - Josephine Lusk AU - Erin Ogilvie AU - Tobias Vickers AU - Don Smith AU - Andrew Grulich TI - P435 Use of condoms for the prevention of Sexually Transmitted Infections (STIs) among HIV Pre-Exposure Prophylaxis (PrEP) users AID - 10.1136/sextrans-2019-sti.521 DP - 2019 Jul 01 TA - Sexually Transmitted Infections PG - A206--A206 VI - 95 IP - Suppl 1 4099 - http://sti.bmj.com/content/95/Suppl_1/A206.2.short 4100 - http://sti.bmj.com/content/95/Suppl_1/A206.2.full SO - Sex Transm Infect2019 Jul 01; 95 AB - Background HIV PrEP is highly effective at preventing HIV, but not STI, acquisition. We examined the use of condoms to prevent STIs among PrEP-users in the EPIC-NSW trial.Methods Between March 2016 and April 2018, 9,708 individuals were enrolled. Analysis was restricted to participants who completed the optional end-of-study survey and were on-study for ≥1 year prior. STI diagnoses came from medical records; other data were from the end-of-study survey. We used multivariate logistic regression to assess independent associations between those agreeing with the statement, “I use condoms to avoid getting STIs” (“STI-condom-users”) and those disagreeing.Results 2,915 participants were included; 92.5% were gay men. In the previous year, 54.2%, 25.6%, and 20.2% were diagnosed with no, one, and ≥2 STIs, respectively. 1,127 (38.7%) reported being STI-condom-users. In multivariate analysis, there was no difference in mean STIs diagnosed in the previous year (0.7 vs 0.8, p=0.244). STI-condom-users were younger (39 vs 41 years, p=0.004), less likely to live in a suburb with ≥10% gay men (24.8% vs 35.5%, p<0.001), less likely to report any condomless sex in the previous 6 months (85.9% vs 93.3%, p<0.001), and had been on-study less time (1.4 vs 1.6 years, p=0.003). STI-condom-users were more: concerned about acquiring STIs (95.1% vs 88.9%, p=0.025), likely to discuss STI results with partners (88.3% vs 79.8%, p<0.001), and likely to believe condoms prevent STI transmission (96.7% vs 89.6%, p<0.001). Fewer STI-condom-users had rejected a sexual partner for wanting to use condoms (9.6% vs 32.7%, p<0.001), while more had been rejected for wanting to use condoms (45.0% vs 26.2%, p<0.001).Conclusion Most PrEP-users did not use condoms for STI prevention, despite strong beliefs in its effectiveness. STI-condom-users did not have fewer STIs, reflecting high levels of condomless sex. Our results suggest alternative methods of STI prevention should be trialled for PrEP-users.Disclosure No significant relationships.