RT Journal Article SR Electronic T1 Characterising HIV and STIs among transgender female sex workers: a longitudinal analysis JF Sexually Transmitted Infections JO Sex Transm Infect FD BMJ Publishing Group Ltd SP 226 OP 231 DO 10.1136/sextrans-2019-054414 VO 97 IS 3 A1 Poteat, Tonia A1 White, Rebecca Hamilton A1 Footer, Katherine H A A1 Park, Ju Nyeong A1 Galai, Noya A1 Huettner, Steven A1 Silberzahn, Brad E A1 Allen, Sean T A1 Glick, Jennifer A1 Beckham, S Wilson A1 Gaydos, Charlotte A A1 Sherman, Susan G YR 2021 UL http://sti.bmj.com/content/97/3/226.abstract AB Objectives Though highly vulnerable to HIV and STIs, transgender female sex workers (TFSWs) are understudied in the US HIV and STI response. This study examined the correlates of laboratory-confirmed STIs among a cohort of 62 TFSWs followed over the course of 1 year and explored associations between specimen site and self-reported engagement in insertive and receptive anal intercourse.Methods Participants completed an interviewer-administered computer-assisted personal interview at baseline, 3-, 6-, 9- and 12-month visits where self-administered anal swabs and urine samples for gonorrhea, chlamydia and trichomoniasis were also collected. HIV testing was conducted at baseline, 6-month and 12-month visits.Results Baseline HIV prevalence was 40.3% with no HIV seroconversions over follow-up. Baseline prevalence of gonorrhea, chlamydia and trichomoniasis was 9.7%, 17.7% and 14.5%, respectively. In the multivariable regression modelling, recent arrest was significantly associated with testing positive for any STI (adjusted risk ratio (RR) 1.77; 95% CI: 1.10 to 2.84). Insertive anal sex with clients was associated with increased risk of testing positive for an STI via urine specimen (RR 3.48; 95% CI: 1.14 to 10.62), while receptive anal sex was not significantly associated with specimen site.Conclusion Our findings confirm a high prevalence of STIs among TFSWs and highlight the importance of addressing structural drivers such as criminal justice involvement as well as the need to ensure screening for STIs at all anatomical sites regardless of self-reported sites of potential exposure. More research is needed to better understand HIV and STI vulnerabilities and appropriate interventions for TFSWs in the USA.Deidentified participant data are available from SSG at Johns Hopkins University: https://orcid.org/0000-0001-8399-7544 on reasonable request and review after submission of a manuscript concept form.