Estimates and ranges used for the sensitivity analysis of the cost effectiveness of a universal screening programme for asymptomatic Chlamydia trachomatis infections in a female population
Variable | Estimate (%) | Range | Domain | References |
---|---|---|---|---|
*Discounted in the model by the age specific desire for pregnancy. | ||||
LCR = ligase chain reaction, PID = pelvic inflammatory disease. | ||||
Prevalence | 2.9 | — | All women | Study data |
Sensitivity LCR | 85 | 85–90 | Tested women | 9, 10 |
Specificity LCR | 99 | — | Tested women | 8, 10 |
Contacted for treatment | 90 | — | Women with chlamydia | Study data |
Successfully treated | 95 | — | Women with chlamydia, who receive treatment | Study data |
All PID | 10 | 5–25 | Women with undiagnosed or unsuccessfully treated infection | 4, 13 |
Asymptomatic of total PID | 50 | — | All PID | 14 |
Preventable PID | 50 | 25–75 | All PID | 14 |
Infertility | 8 | 4–16 | All PID* | 1 |
Ectopic pregnancy | 8 | 4–16 | All PID* | 1 |
Chronic pelvic pain | 15 | 10–20 | All PID | 2 |
Neonatal conjunctivitis | 30 | — | Women with chlamydia* | 3 |
Neonatal pneumonia | 15 | — | Women with chlamydia* | 3 |