Combined colposcopy results
| Number of participants (*) with finding | ||||
|---|---|---|---|---|
| Assessment | Predose | Week 1 | Week 2 | Postdose |
| *N = 24 in the treatment groups; N = 25 in the placebo arm. | ||||
| †Ecchymosis, petechial haemorrhage, and/or subepithelial haemorrhage with swelling. | ||||
| ‡In Antwerp a vulvar ulceration was diagnosed on day 4 for participant 01/02. | ||||
| Cervicovaginal ulcer: | ||||
| 4% PRO 2000 gel | 0 | 0‡ | 0 | 1 |
| 0.5% PRO 2000 gel | 0 | 0 | 0 | 3 |
| Placebo gel | 0 | 0 | 0 | 0 |
| Cervicovaginal abrasion: | ||||
| 4% PRO 2000 gel | 1 | 3 | 2 | 2 |
| 0.5% PRO 2000 gel | 1 | 1 | 0 | 0 |
| Placebo gel | 0 | 0 | 1 | 2 |
| Subepithelial haemorrhage†: | ||||
| 4% PRO 2000 gel | 1 | 6 | 6 | 3 |
| 0.5% PRO 2000 gel | 0 | 2 | 4 | 3 |
| Placebo gel | 2 | 3 | 2 | 2 |
| Erythema/oedema: | ||||
| 4% PRO 2000 gel | 0 | 10 | 4 | 1 |
| 0.5% PRO 2000 gel | 0 | 5 | 5 | 0 |
| Placebo gel | 1 | 2 | 4 | 2 |