Hepatitis A | IgM anti-HAV+ve | Does not occur | IgG anti-HAV +ve IgM anti-HAV -ve |
Hepatitis B | IgM anti-HBc +ve, HBsAg +ve, HBeAg +ve HBV-DNA +ve | IgM anti-HBc -ve (+ve low titre in flares) HBsAg +ve, HBeAg + or -ve HBV-DNA+ or -ve | IgG anti-HBc +ve (NB some tests measure combined IgG and IgM) IgG anti-HBs +ve (may become negative) HBsAg -ve |
Hepatitis C | IgG anti-HCV +ve by ELISA and RIBA tests (but may take up to 3 months or more). HCV-RNA +ve by PCR | As for acute infection | Antibody negative or IgG anti-HCV +ve by ELISA and RIBA tests. HCV-RNA -ve by PCR |
Hepatitis D | IgG and IgM anti-HDV +ve HDAg +ve, HDV-RNA +ve With markers of acute/chronic hepatitis B infection | As for acute infection | Antibody, antigen, and RNA tests become negative within months of recovery. |