A (evidence levels Ia, Ib) | Requires at least one randomised, controlled trial as part of the body of literature of overall good quality and consistency addressing the specific recommendation |
B (evidence levels IIa, IIb, III) | Requires availability of well conducted clinical studies but no randomised clinical trials on the topic of recommendation |
C (evidence level IV) | Requires evidence from expert committee reports or opinions and/or clinical experience of respected authorities. Indicates absence of directly applicable studies of good quality |