Type I Immediate hypersensitivity |
Dependent on the specific triggering of IgE sensitised mast cells by antigen—for example, asthma, hay fever, urticaria, anaphylaxis |
Type II |
Antibody is directed against antigens on specific host cells and tissues—for example, graft rejection, autoimmuine haemolytic anaemia, myasthenia gravis |
Type III |
Antigen-antibody complexes are deposited in tissues—for example, rheumatoid arthritis, systemic lupus erythematosus, serum sickness, infective endocarditis, malaria |
Type IV Delayed hypersensitivity |
Antigen sensitisred T cells release cytokines following secondary contact with the same antigen—for example, contact dermatitis, tuberculosis, leprosy |