Univariate associations between HSV type and demographic, clinical, and behavioural variables
| Variable | HSV-1 | HSV-2 | Odds ratio | 95% CI | p Value† | |||
|---|---|---|---|---|---|---|---|---|
| No | % | No | % | |||||
| †Pearson’s χ2 p value, except where otherwise indicated. ‡Fisher’s exact test, two tailed p value. ND, not determined because of zero cells. | ||||||||
| Sex | ||||||||
| Male | 20 | 3.5 | 555 | 96.5 | Referent | |||
| Female | 19 | 5.3 | 341 | 94.7 | 1.55 | (0.81 to 2.94) | 0.18 | |
| Age | ||||||||
| <20 | 1 | 2.9 | 33 | 97.1 | Referent | |||
| 20–29 | 19 | 5.1 | 352 | 94.9 | 1.78 | (0.23 to 13.73) | 1.0‡ | |
| 30–39 | 9 | 2.9 | 296 | 97.1 | 1.00 | (0.12 to 8.17) | 1.0‡ | |
| 40–49 | 8 | 4.8 | 158 | 95.2 | 1.67 | (0.20 to 13.82) | 1.0‡ | |
| 50–59 | 2 | 3.8 | 50 | 96.2 | 1.32 | (0.12 to 15.15) | 1.0‡ | |
| 60+ | 0 | 0 | 12 | 100 | ND | ND | 1.0‡ | |
| Race | ||||||||
| White | 29 | 6.5 | 418 | 93.5 | Referent | |||
| Black | 5 | 1.3 | 390 | 98.7 | 0.18 | (0.07 to 0.48) | <0.01 | |
| Other | 5 | 5.3 | 90 | 94.7 | 0.80 | (0.30 to 2.13) | 0.65 | |
| Ethnicity | ||||||||
| Non-Hispanic | 34 | 4.2 | 785 | 95.9 | Referent | |||
| Hispanic | 4 | 4.2 | 92 | 95.8 | 1.00 | (0.35 to 2.89) | 1.0‡ | |
| Duration of previous lesion | ||||||||
| 0–5 days | 14 | 3.7 | 369 | 96.3 | Referent | |||
| 6–7 days | 11 | 4.0 | 265 | 96.0 | 1.09 | (0.49 to 2.45) | 0.83 | |
| 8–10 days | 5 | 4.5 | 107 | 95.5 | 1.23 | (0.43 to 3.50) | 0.70 | |
| 11+ days | 9 | 5.3 | 160 | 94.7 | 1.48 | (0.63 to 3.50) | 0.37 | |
| Episodes in previous 12 months | ||||||||
| 0–2 | 19 | 9.1 | 191 | 90.9 | Referent | |||
| 3–4 | 17 | 3.4 | 484 | 96.6 | 0.35 | (0.18 to 0.69) | <0.01 | |
| 5+ | 3 | 1.3 | 226 | 98.7 | 0.13 | (0.04 to 0.46) | <0.01 | |
| Years since 1st genital herpes lesion | ||||||||
| 1 or less | 17 | 4.3 | 382 | 95.7 | Referent | |||
| 2–5 | 15 | 5.5 | 258 | 94.5 | 1.31 | (0.64 to 2.66) | 0.46 | |
| 6+ | 7 | 2.6 | 261 | 97.4 | 0.60 | (0.25 to 1.47) | 0.26 | |
| Ever used anti-herpes drugs | ||||||||
| No | 20 | 3.9 | 499 | 96.2 | Referent | |||
| Yes | 18 | 4.4 | 387 | 95.6 | 1.16 | (0.61 to 2.22) | 0.65 | |
| Aciclovir resistant isolate | ||||||||
| No | 39 | 4.2 | 886 | 95.8 | Referent | |||
| Yes | 0 | 0 | 15 | 100 | ND | ND | 1.0‡ | |
| HIV status | ||||||||
| Negative | 31 | 4.0 | 746 | 96.0 | Referent | |||
| Positive | 8 | 5.0 | 152 | 95.0 | 1.27 | (0.57 to 2.81) | 0.56 | |
| Sex partners in previous 12 months | ||||||||
| None | 4 | 3.9 | 99 | 96.1 | Referent | |||
| Opposite sex only | 28 | 3.8 | 716 | 96.2 | 0.97 | (0.33 to 2.82) | 1.0‡ | |
| Same sex only | 7 | 9.9 | 64 | 90.1 | 2.71 | (0.76 to 9.62) | 0.12‡ | |
| Both | 0 | 0 | 22 | 100 | ND | ND | 1.0‡ | |
| Lesion site | ||||||||
| Women only | ||||||||
| Vulva | 11 | 6.4 | 160 | 93.6 | Referent | |||
| Cervico-vaginal | 3 | 5.8 | 49 | 94.2 | 0.89 | (0.24 to 3.32) | 1.0‡ | |
| Rectal/perirectal | 3 | 7.3 | 38 | 92.7 | 1.15 | (0.31 to 4.32) | 0.74‡ | |
| Thigh | 1 | 1.2 | 61 | 98.4 | 0.24 | (0.03 to 1.89) | 0.19‡ | |
| Other | 0 | 0 | 14 | 100 | ND | ND | 1.0‡ | |
| Multiple sites | 1 | 7.1 | 13 | 92.9 | 1.12 | (0.13 to 9.36) | 1.0‡ | |
| Men only | ||||||||
| Penis | 11 | 2.5 | 434 | 97.5 | Referent | |||
| Rectal/perirectal | 9 | 13.2 | 59 | 86.8 | 6.02 | (2.39 to 3.32) | <0.01‡ | |
| Thigh | 0 | 0 | 37 | 100 | ND | ND | 1.0‡ | |
| Other | 0 | 0 | 19 | 100 | ND | ND | 1.0‡ | |
| Multiple sites | 0 | 0 | 3 | 100 | ND | ND | 1.0‡ | |