Patient flow chart and efficacy at 12 weeks for oral isotretinoin 0.5 mg/kg/day (group 1) versus placebo (group 2)
| Group 1 | Group 2 | |
|---|---|---|
| No of patients entered | 30 | 30 |
| No of patients withdrawn (side effects or poor compliance) | 2 | 2 |
| No of patients lost to follow up | 0 | 3 |
| No of evaluable patients | 28 | 25 |
| Response | ||
| Complete response | 9 (32.1%) | 0 (0%) |
| Partial response | 11 (39.2%) | 2 (8%) |
| No response | 8 (28.5%) | 23 (92%) |
| Mean area of the lesions (mm2) | ||
| Before treatment (SD) | 13.1 (5.4) | 12.8 (4.7) |
| After treatment (SD) | 6.9 (3.8) | 11.9 (4.4) |