Projected impact over 4 years (1995–8) of the STI treatment aspect of the SIDA2 HIV prevention intervention, for its current method of syndromic diagnosis and if it had used POC tests
| Diagnostic test used for Ng/Ct | FSW Ng/Ct screening | FSW clinic attenders treated for Ng/Ct at SIDA2 clinic | Total Ng/Ct averted [prevented fraction*] | Total HIV averted [prevented fraction*] | Infections averted per FSW treated at clinic | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Sensitivity | Specificity | Correctly | Incorrectly | Mean | (95% CI) | Mean | (95% CI) | Ng/Ct | HIV | |
| Numbers in parentheses are uncertainty bounds. | ||||||||||
| *Prevented fraction refers to the percentage of incident infections that are averted as a result of the STI treatment intervention | ||||||||||
| Syndromic algorithm | 48% | 75% | 1339 (1181–1709) | 1861 (1668–1966) | 18 553 [10%] | (16 871–20 447) (8% to 13%) | 359 [6%] | (220–464) (4% to 8%) | 5.8 (5.2–6.2) | 0.11 (0.07–0.14) |
| POC test | 60% | 95% | 1620 (1423–2081) | 377 (338–398) | 22 882 [13%] | (20 766–25 307) (10% to 16%) | 442 [8%] | (272–572) (5% to 10%) | 11.5 (10.2–12.4) | 0.22 (0.12–0.29) |
| POC test | 70% | 95% | 1840 (1610–2375) | 381 (342–402) | 26 395 [15%] | (23 913–29 278) (12% to 18%) | 509 [9%] | (314–660) (6% to 11%) | 11.9 (10.6–12.9) | 0.23 (0.13–0.31) |
| POC test | 80% | 95% | 2046 (1785–2655) | 384 (346–406) | 29 823 [17%] | (26 970–33 180) (13% to 20%) | 575 [10%] | (355–746) (6% to 12%) | 12.3 (10.9–13.3) | 0.24 (0.13–0.32) |