Table 2

 Summary of studies

NoAuthorPap smearRecruitment siteNoPatient collection deviceCriterion standardDignostic methodHPV typesSensitivity (95% CI)Specificity (95% CI)+LR− LRORKappa
ABN, women with normal and abnormal Pap smears included; Sx, women with symptoms of, contacts of, or at risk for sexually transmitted infections included; CVL, cervicovaginal lavage; HC-II, Digene Hybrid Capture-II technology; PCR, polymerase chain reaction; +LR, positive likelihood ratio; −LR, negative likelihood ratio; OR, odds ratio; HR, high risk.
1Sellors17ABNColposcopy200Dacron swabCone-shaped brushHC-IIHR0.87 (0.8 to 0.92)0.91 (0.81 to 0.96)9.670.1460.60.76
2Hillemanns 18ABNColposcopy247CytobrushCytobrushHC-IIBoth0.90 (0.82 to 0.95)0.79 (0.72 to 0.85)4.290.1333.650.66
3Harper26ABNGynaecology93TamponDacron swabHC-IIBoth0.67 (0.45 to 0.83)0.84 (0.73 to 0.91)4.190.399.870.49
4Nobbenhuis23ABNColposcopy54CVLCervex brushPCRHR0.71 (0.55 to 0.84)1.00 (0.74 to 1.00)17.750.30610.53
5Morrison 19ABNColposcopy16CVLNot statedPCRBoth1.00 (0.77 to 1.00)1.00 (0.16 to 1.00)5.650.051451.00
6Wright21No PapOutreach1415Dacron swabCone-shaped brushHC-IIHR0.56 (0.50 to 0.62)0.88 (0.86 to 0.9)4.670.59.870.45
7Rompalo20SxPrimary care319Dacron swabDacron swabPCRBoth0.64 (0.55 to 0.73)0.84 (0.78 to 0.88)40.439.000.48
8Chang24No PapOutreach1194CottonNot statedHC-IIHR0.93 (0.87 to 0.96)1.00 (1.00 to 1.00)930.0726123.090.96
9Harper25ABNColposcopy103Dacron swabDacron swabPCRBoth0.78 (0.60 to 0.89)0.94 (0.85 to 0.98)130.2347.310.74
10Lorenzato27ABNColposcopy253Cotton swabCytobrushPCRBoth0.63 (0.50 to 0.73)0.94 (0.90 to 0.97)10.50.3927.020.62
11Fairley28ABNColposcopy48TamponAyre SpatulaPCRBoth0.89 (0.72 to 0.96)0.85 (0.54 to 0.97)5.930.1332.200.7
12Coutlee29HIV+/HIV-womenHIV clinicsSTD clinics270TamponCVLPCRBoth0.94 (0.88 to 0.97)0.80 (0.72 to 0.87)4.70.07559.210.75