Laboratory profile in relation to diagnosis and treatment
At initial diagnosis | On HAART | 8 weeks off therapy | ||||
---|---|---|---|---|---|---|
Age | 10 months | 49 months | 57 months | |||
HIV-1 ELISA | Positive | Negative | Positive | |||
Raw optical density | ||||||
Cut off | Not available | 0.27 | 0.27 | 0.28 | 0.29 | |
Positive control (PC) | Not available | 1.77 | 1.85 | 2.1 | 2.0 | |
Negative control | Not available | 0.02 | 0.02 | 0.03 | 0.04 | |
External low PC | Not available | 0.87 | 0.68 | 0.94 | 0.88 | |
Patient | Not available | 0.26 | 0.23 | 2.34 | 2.38 | |
Patient/cut off ratio (>1 = positive, <1 = negative) | Not available | 0.94 | 0.83 | 8.3 | 8.0 | |
Western blot | Positive | Negative | Positive | |||
Visible bands | ||||||
gp160 | Not available | Absent | Present | |||
gp120 | Not available | Absent | Present | |||
gp41 | Not available | Absent | Present | |||
p24 | Not available | “+/−” (Band intensity < gp120 in the Weak Positive Control) | Present | |||
DNA PCR | Positive | Negative | Positive | |||
RNA PCR (copies/ml) | >5 log10 | <400 | >5 log10 | |||
CD4 count (cells ×106/l) | Not available | 1209 (36%) | 716 (26%) |