Patients (n) | 15 | 24 | |
Age (years), median (IQR) | 34 (26–38) | 39 (34–43) | 0.008 |
Ethnicity (Dutch) | 11/15 (73%) | 18/24 (75%) | 0.91 |
| | | |
Sexual orientation | | | 0.30 |
Male homosexual | 12/15 (80%) | 22/24 (92%) | |
Male bisexual | 3/15 (20%) | 2/24 (8%) | |
| | | |
HIV serostatus | | | 0.057 |
HIV positive | 7/15 (47%) | 20/24 (83%) | |
HIV negative | 6/15 (40%) | 4/24 (17%) | |
Unknown | 2/15 (13%) | — | |
| | | |
CD4 count (in cells/µl), median (IQR) | 370 (370–520) | 525 (420–655) | 0.22 |
History of chlamydial infection | 3/15 (20%) | 6/23 (26%) | 0.85 |
Concomitant STI | 6/15 (40%) | 8/24 (33%) | 0.67 |
Antibodies against HCV | 0/5 (0%) | 4/24 (17%) | <0.001 |
Newly detected HIV infection | 5/15 (33%) | 3/24 (13%) | 0.12 |
New STI within first year | 1/12 (8%) | 5/22 (23%) | 0.16 |
CRP at the time of detection, median (IQR) | 1 (1–3) | 2 (1–14) | 0.073 |
| | | |
IgA at the time of detection, median (IQR) | 0.6 (0.5–1.0) | 3.5 (2.3–5.0) | <0.001 |
IgG at the time of detection, median (IQR) | 2.3 (0.7–3.7) | 5.3 (4.0–6.9) | <0.001 |
| | | |
IgA specimen classification “negative” | 11/15 (73%) | 2/24 (8%) | <0.001 |
Measurable ratio | 4/15 (27%) | 15/24 (63%) | 0.027 |
Greater than measurable ratio | 0/15 (0%) | 7/24 (29%) | 0.005 |
| | | |
IgG specimen classification “negative” | 5/15 (33%) | 0/24 (0%) | 0.001 |
Measurable ratio | 9/15 (60%) | 5/24 (21%) | 0.013 |
Greater than measurable ratio | 1/15 (7%) | 19/24 (79%) | <0.001 |
| | | |
| n = 10 | n = 17 | |
IgA after 6 months, median (IQR) | 0.4 (0.3–1.1) | 3.1 (1.2–5.3) | <0.001 |
IgG after 6 months, median (IQR) | 1.5 (1.1–3.2) | 5.4 (4.2–6.6) | 0.001 |
| | | |
| n = 6 | n = 9 | |
IgA after 1 year (median, IQR) | 0.7 (0.5–0.9) | 4.3 (0.9–6.1) | 0.003 |
IgG after 1 year, median (IQR) | 2.2 (1.2–3.5) | 5.4 (3.7–6.5) | 0.012 |