Table 1

 Demographics, sexual orientation, HIV status, concomitant sexually transmitted infection (STI) and titres of IgA and IgG antibodies in patients with rectal Chlamydia trachomatis infection attending the Erasmus MC STI clinic

Non-LGVLGVp Value
CRP, C reactive protein; HCV, hepatitis C virus; IQR, interquartile range; STI, sexually transmitted infection.
Patients (n)1524
Age (years), median (IQR)34 (26–38)39 (34–43)0.008
Ethnicity (Dutch)11/15 (73%)18/24 (75%)0.91
Sexual orientation0.30
    Male homosexual12/15 (80%)22/24 (92%)
    Male bisexual3/15 (20%)2/24 (8%)
HIV serostatus0.057
    HIV positive7/15 (47%)20/24 (83%)
    HIV negative6/15 (40%)4/24 (17%)
    Unknown2/15 (13%)—
CD4 count (in cells/µl), median (IQR)370 (370–520)525 (420–655)0.22
History of chlamydial infection3/15 (20%)6/23 (26%)0.85
Concomitant STI6/15 (40%)8/24 (33%)0.67
Antibodies against HCV0/5 (0%)4/24 (17%)<0.001
Newly detected HIV infection5/15 (33%)3/24 (13%)0.12
New STI within first year1/12 (8%)5/22 (23%)0.16
CRP at the time of detection, median (IQR)1 (1–3)2 (1–14)0.073
IgA at the time of detection, median (IQR)0.6 (0.5–1.0)3.5 (2.3–5.0)<0.001
IgG at the time of detection, median (IQR)2.3 (0.7–3.7)5.3 (4.0–6.9)<0.001
IgA specimen classification “negative”11/15 (73%)2/24 (8%)<0.001
     Measurable ratio4/15 (27%)15/24 (63%)0.027
     Greater than measurable ratio0/15 (0%)7/24 (29%)0.005
IgG specimen classification “negative”5/15 (33%)0/24 (0%)0.001
    Measurable ratio9/15 (60%)5/24 (21%)0.013
     Greater than measurable ratio1/15 (7%)19/24 (79%)<0.001
n = 10n = 17
IgA after 6 months, median (IQR)0.4 (0.3–1.1)3.1 (1.2–5.3)<0.001
IgG after 6 months, median (IQR)1.5 (1.1–3.2)5.4 (4.2–6.6)0.001
n = 6n = 9
IgA after 1 year (median, IQR)0.7 (0.5–0.9)4.3 (0.9–6.1)0.003
IgG after 1 year, median (IQR)2.2 (1.2–3.5)5.4 (3.7–6.5)0.012