Performance of diagnostic tests for T vaginalis (n = 119)*
| Assay or test | Number of tests | % Sensitivity(95% CI) | % Specificity(95% CI) | |||
|---|---|---|---|---|---|---|
| True positive | False positive | False negative | True negative | |||
| PCR, polymerase chain reaction. | ||||||
| *The gold standard was a positive culture result using vaginal swabs and/or a positive PCR test using TVK3/7 primers (n = 78). | ||||||
| †Includes all 34 culture-positive specimens. | ||||||
| ‡Six culture-positive specimens were negative by this assay. | ||||||
| §One culture-positive specimen was negative by this assay. | ||||||
| Culture, vaginal swab | 34 | 0 | 44 | 41 | 43.6 (32.4 to 55.3) | 100 (91.4 to 100) |
| Wet preparation, vaginal swab | 34 | 1 | 44 | 40 | 43.6 (32.4 to 55.3) | 97.6 (87.1 to 99.9) |
| Conventional PCR | ||||||
| Vaginal washing | 78† | 0 | 0 | 41 | 100 (95.4 to 100) | 100 (91.4 to 100) |
| Urine | 44‡ | 1 | 34 | 40 | 56.4 (44.7 to 67.6) | 97.6 (87.1 to 99.9) |
| Real-time PCR | ||||||
| Vaginal washing | 78† | 7 | 0 | 34 | 100 (95.4 to 100) | 82.9 (67.9 to 92.8) |
| Urine | 66§ | 1 | 20 | 32 | 76.7 (66.4 to 85.2) | 97.0 (84.2 to 99.9) |