| Visit number | HSV-2 shedding | Not HSV-2 shedding | ||
| Acyclovir | Placebo | Acyclovir | Placebo | |
| 1 | 3/4 (75) | 9/12 (75) | 41/54 (76) | 26/39 (67) |
| 2 | 2/3 (67) | 7/13 (54) | 38/39 (64) | 22/34 (65) |
| 3 | 0/1 (0) | 8/12 (67) | 25/53 (49) | 19/37 (51) |
| 4 | 6/6 (100) | 5/9 (56) | 30/48 (63) | 17/34 (50) |
| 5 | 8/9 (89) | 7/11 (64) | 31/49 (63) | 20/36 (56) |
| 6 | 6/7 (86) | 6/7 (86) | 29/45 (64) | 17/32 (53) |
| 7 | 5/6 (83) | 6/9 (67) | 25/48 (52) | 23/35 (66) |
| 8 | 6/6 (100) | 5/6 (83) | 32/46 (70) | 22/33 (67) |
| 9 | 3/3 (100) | 7/9 (78) | 30/46 (65) | 18/31 (58) |
| 10 | 6/6 (100) | 13/13 (100) | 33/47 (70) | 18/32 (56) |
| 11 | 6/7 (86) | 8/10 (80) | 27/42 (64) | 20/34 (59) |
| 12 | 6/6 (100) | 9/11 (82) | 31/44 (70) | 20/31 (65) |
| Overall HIV shedding rate | 57/64 (89%) | 90/122 (74%) | 373/581 (64%) | 242/480 (59%) |
HSV-2, herpes simplex virus type 2.