Risk of developing complications following acute chlamydial infection
| Complication | Probability (sample size) | Probability applied to: | Distribution type | Reference | |
|---|---|---|---|---|---|
| PID, pelvic inflammatory disease, EP, ectopic pregnancy. *All screening strategies were run with all three probabilities. †Based on the number of women trying to conceive, after a laparoscopically diagnosed PID case, the total denotes the total number followed up. ‡The total is the number of infants exposed at birth. | |||||
| Symptomatic PID (women) | 1%, 10%, 30% | Asymptomatic chlamydial infection | Scenario analysis* | Assumption | |
| Ectopic pregnancy (women) | 7.6% (1309)† | Symptomatic PID | Beta | Weström et al9 | |
| Tubal factor infertility (women) | 10.8% (1309)† | Symptomatic PID (exclude those with EP) | Beta | Weström et al9 | |
| Neonatal conjunctivitis | 14.8% (1055)‡ | Infected women giving birth vaginally | Beta | Rosenman et al18 | |
| Neonatal pneumonia | 7.0% (597)‡ | Infected women giving birth vaginally | Beta | Rosenman et al18 | |
| Epididymitis (men) | 2% | Asymptomatic chlamydial infection | Fixed | Assumption based on work by Welte et al19,20 | |