Total MO | Total QALYs lost | Total cost (£) | Incremental cost (£)/MOA | Incremental cost (£)/QALY gained | Average cost (£)/MOA | Average cost (£)/QALY gained | |
---|---|---|---|---|---|---|---|

MO, major outcome; MOA, major outcomes averted. Values in the table are rounded for presentation. QALY, quality adjusted life years; All costs and effects are discounted at 3.5%. Results are presented in rank order of total costs, which include costs of infection, complications, and programme costs. Dominated means that the MOA or QALYs gained is less than the non-dominated strategy above it in the table. | |||||||

Baseline, noscreening | 393 | 10 | 108 408 | – | – | – | – |

Strategy 1 <20 | 256 | 6 | 430 991 | 2364 | 84 337 | 2364 | 84 337 |

Strategy 2 <20 | 222 | 5 | 670 680 | 7118 | 241 271 | 3305 | 116 693 |

Strategy 3 <20 | 201 | 5 | 739 267 | 3125 | 149,745 | 3284 | 119 562 |

Strategy 1 <25 | 215 | 5 | 811 689 | Dominated | Dominated | 3960 | 139 219 |

Strategy 1 <30 | 203 | 5 | 1 196 464 | Dominated | Dominated | 5754 | 207 198 |

Strategy 2 <25 | 171 | 4 | 1 378 328 | 21 573 | 736 387 | 5728 | 206 685 |

Strategy 3 <25 | 137 | 3 | 1 494 862 | 3474 | 157 304 | 5432 | 201 371 |

Strategy 1 <35 | 189 | 4 | 1 577 516 | Dominated | Dominated | 7204 | 262 845 |

Strategy 1 <40 | 185 | 4 | 1 959 279 | Dominated | Dominated | 8905 | 326 900 |

Strategy 2 <30 | 149 | 3 | 2 088 871 | Dominated | Dominated | 8122 | 296 053 |

Strategy 3 <30 | 114 | 3 | 2 253 126 | 32 374 | 1 544 567 | 7696 | 290 770 |

Strategy 2 <35 | 140 | 3 | 2 799 862 | Dominated | Dominated | 10 657 | 389 895 |

Strategy 3 <35 | 104 | 2 | 3 015 808 | 75 208 | 3 161 809 | 10 067 | 381 688 |

Strategy 2 <40 | 133 | 3 | 3 517 839 | Dominated | Dominated | 13 157 | 485 712 |

Strategy 3 <40 | 94 | 2 | 3 773 363 | 76 841 | 6 909 379 | 12 271 | 474 314 |