Total MO | Total QALYs lost | Total cost (£) | Incremental cost(£)/MOA | Incremental cost (£)/QALY gained | Average cost (£)/MOA | Average cost (£)/QALY gained | |
---|---|---|---|---|---|---|---|

MO, major outcome; MOA, major outcomes averted. Values in the table are rounded for presentation. QALY, quality adjusted life years; All costs and effects are discounted at 3.5%. Results are presented in rank order of total costs, which include costs of infection, complications, and programme costs. Dominated means that the MOA or QALYs gained is less than the non-dominated strategy above it in the table. | |||||||

Baseline, noscreening | 1392 | 65 | 310 695 | – | – | – | – |

Strategy 1 <20 | 883 | 39 | 553 352 | 477 | 9204 | 477 | 9204 |

Strategy 2 <20 | 736 | 31 | 771 367 | 1484 | 29 416 | 703 | 13 640 |

Strategy 3 <20 | 673 | 29 | 832 498 | 959 | 24 103 | 726 | 14 371 |

Strategy 1 <25 | 739 | 32 | 918 213 | Dominated | Dominated | 930 | 18 476 |

Strategy 1 <30 | 645 | 28 | 1 283 628 | 16 415 | 978 039 | 1303 | 26 459 |

Strategy 2 <25 | 584 | 24 | 1 462,494 | 2928 | 44 109 | 1426 | 28 212 |

Strategy 3 <25 | 468 | 19 | 1 556 572 | 807 | 19 352 | 1348 | 27 269 |

Strategy 1 <35 | 633 | 28 | 1 666 599 | Dominated | Dominated | 1788 | 36 849 |

Strategy 1 <40 | 610 | 28 | 2 048 769 | Dominated | Dominated | 2224 | 46 404 |

Strategy 2 <30 | 491 | 20 | 2 157 585 | Dominated | Dominated | 2051 | 41 470 |

Strategy 3 <30 | 400 | 17 | 2 308 023 | 11 059 | 302 328 | 2013 | 41 461 |

Strategy 2 <35 | 460 | 20 | 2 869 275 | Dominated | Dominated | 2745 | 56 481 |

Strategy 3 <35 | 363 | 16 | 3 064 432 | 20 479 | 747 964 | 2676 | 55 987 |

Strategy 2 <40 | 444 | 20 | 3 582 115 | Dominated | Dominated | 3453 | 71 953 |

Strategy 3 <40 | 343 | 15 | 3 828 432 | 39 230 | 1 938 410 | 3355 | 70 952 |