Total MO | Total QALYs lost | Total cost (£) | Incremental cost (£)/MOA | Incremental cost (£)/QALY gained | Average cost (£)/MOA | Average cost (£)/QALY gained | |
---|---|---|---|---|---|---|---|

MO, major outcome; MOA, major outcomes averted. Values in the table are rounded for presentation. QALY, quality adjusted life years; All costs and effects are discounted at 3.5%. Results are presented in rank order of total costs, which include costs of infection, complications, and programme costs. Dominated means that the MOA or QALYs gained is less than the non-dominated strategy above it in the table. | |||||||

Baseline, noscreening | 3529 | 156 | 709 068 | – | – | – | – |

Strategy 1 <20 | 2216 | 92 | 796 042 | 66 | 1364 | 66 | 1364 |

Strategy 2 <20 | 1878 | 75 | 974 854 | 529 | 10 402 | 161 | 3283 |

Strategy 3 <20 | 1676 | 66 | 1 008 678 | 168 | 3845 | 162 | 3338 |

Strategy 1 <25 | 1799 | 75 | 1 110 924 | Dominated | Dominated | 232 | 4960 |

Strategy 1 <30 | 1641 | 70 | 1 466 413 | 13 279 | Dominated | 401 | 8799 |

Strategy 2 <25 | 1397 | 55 | 1 600 015 | 546 | 53 317 | 418 | 8834 |

Strategy 3 <25 | 1195 | 46 | 1 682 280 | 407 | 8961 | 417 | 8845 |

Strategy 1 <35 | 1574 | 68 | 1 842 956 | Dominated | Dominated | 580 | 12 987 |

Strategy 1 <40 | 1508 | 66 | 2 213 265 | Dominated | Dominated | 744 | 16 829 |

Strategy 2 <30 | 1200 | 48 | 2 277 375 | Dominated | Dominated | 673 | 14 589 |

Strategy 3 <30 | 1018 | 41 | 2 419 181 | 4181 | 149 930 | 681 | 14 877 |

Strategy 2 <35 | 1138 | 47 | 2 991 631 | Dominated | Dominated | 955 | 21 068 |

Strategy 3 <35 | 909 | 38 | 3 163 011 | 6835 | 238 076 | 937 | 20 783 |

Strategy 2 <40 | 1071 | 46 | 3 696 199 | Dominated | Dominated | 1215 | 27 228 |

Strategy 3 <40 | 852 | 37 | 3 921 645 | 13 304 | 714 049 | 1200 | 26 966 |