Sensitivity of the estimated average cost effectiveness of screening to the choice of intervention parameter
| PID rate | Scenario | Net MOA | Net QALY | Net costs(£) | Cost (£)/MOA | Cost (£)/QALY gained |
|---|---|---|---|---|---|---|
| NSCP, National Chlamydia Screening Programme; PID, pelvic inflammatory disease; MOA, major outcomes averted; QALY, quality adjusted life years; PN, partner notification, F, female; M, male. Under baseline assumptions, screening acceptance is 50%, PN is 20%, and screening is offered annually. | ||||||
| The baseline is the NSCP strategy (strategy 3, annual screen offer to men and women under 25 years old) compared to no screening. | ||||||
| 1% | Screening baseline | 255 | 7 | 1 386 454 | 5432 | 201 371 |
| Acceptance = F, 10%; M,1.4% | 70 | 2 | 1 290 587 | 18 308 | 643 037 | |
| Acceptance = 10% | 117 | 3 | 1 315 002 | 11 240 | 407 440 | |
| Acceptance = 30% | 220 | 6 | 1 356 937 | 6182 | 231 433 | |
| Acceptance = 70% | 275 | 7 | 1 404 474 | 5101 | 190 166 | |
| PN = 50% | 286 | 8 | 1 415 138 | 4953 | 186 321 | |
| Screen only once | 187 | 5 | 530 449 | 2830 | 104 007 | |
| 10% | Screening baseline | 924 | 46 | 1 245 877 | 1348 | 27 269 |
| Acceptance = F, 10%; M, 1.4% | 302 | 15 | 1 241 250 | 4106 | 83 717 | |
| Acceptance = 10% | 443 | 22 | 1 245 655 | 2809 | 57 445 | |
| Acceptance = 30% | 807 | 40 | 1 234 664 | 1530 | 30 869 | |
| Acceptance = 70% | 989 | 49 | 1 256 063 | 1270 | 25 633 | |
| PN = 50% | 1021 | 50 | 1 257 727 | 1232 | 24 966 | |
| Screen only once | 677 | 34 | 429 762 | 635 | 12 814 | |
| 30% | Screening baseline | 2334 | 110 | 973 212 | 417 | 8845 |
| Acceptance = F, 10%; M, 1.4% | 762 | 35 | 1 156 289 | 1518 | 33 241 | |
| Acceptance = 10% | 1121 | 51 | 1 115 870 | 995 | 21 676 | |
| Acceptance = 30% | 2030 | 95 | 1 005 087 | 495 | 10 605 | |
| Acceptance = 70% | 2481 | 117 | 969 306 | 391 | 8320 | |
| PN = 50% | 2599 | 122 | 960 098 | 369 | 7899 | |
| Screen only once | 1735 | 81 | 227 799 | 131 | 2826 | |