Table 2 Prevalence of HPV DNA detected by the Roche Linear Array assay in the anal canal of homosexual men, by HIV serostatus
HPV prevalence, n (%)p Value*
All men (n = 129)HIV-positive (n = 36)HIV-negative (n = 93)
HPV-positive (any type) 122 (94.6)35 (97.2)87 (93.5)0.407
    Any low-risk type†113 (87.6)32 (88.9)81 (87.1)0.781
    Any high-risk type†102 (79.1)34 (94.4)68 (73.1)0.008
    Low- and high-risk types†93 (72.1)31 (86.1)62 (66.7)0.028
    Low-risk only†20 (15.5)1 (2.8)19 (20.4)0.013
    High-risk only†9 (7.0)3 (8.3)6 (6.5)0.719
Low-risk HPV types
    6 or 1148 (37.2)21 (58.3)27 (29.0)0.002
    635 (27.1)14 (38.9)21 (22.6)0.062
    1116 (12.4)8 (22.2)8 (8.6)0.036
    262 (1.6)02 (2.2)0.370
    407 (5.4)4 (11.1)3 (3.2)0.075
    4216 (12.4)6 (16.7)10 (10.8)0.363
    5333 (25.6)10 (27.8)23 (24.7)0.717
    5410 (7.8)1 (2.8)9 (9.7)0.189
    5520 (15.5)8 (22.2)12 (12.9)0.190
    6120 (15.5)4 (11.1)16 (17.2)0.390
    6219 (14.7)4 (11.1)15 (16.1)0.472
    641 (0.8)01 (1.1)0.528
    6612 (9.3)3 (8.3)9 (9.7)0.806
    673 (2.3)2 (5.6)1 (1.1)0.131
    696 (4.7)4 (11.1)2 (2.2)0.032
    7021 (16.3)10 (27.8)11 (11.8)0.027
    712 (1.6)02 (2.2)0.370
    7217 (13.2)6 (16.7)11 (11.8)0.460
    7318 (14.0)8 (22.2)10 (10.8)0.094
    8114 (10.9)7 (19.4)7 (7.5)0.051
    8213 (10.1)7 (19.4)6 (6.5)0.029
    837 (5.4)2 (5.6)5 (5.4)0.964
    8418 (14.0)9 (25.0)9 (9.7)0.025
High-risk HPV types
    16 or 1850 (38.8)14 (38.9)36 (38.7)0.983
    1638 (29.5)13 (36.1)25 (26.9)0.304
    1823 (17.8)6 (16.7)17 (18.3)0.831
    3314 (10.9)5 (13.9)9 (9.7)0.492
    3518 (14.0)10 (27.8)8 (8.6)0.005
    3923 (17.8)10 (27.8)13 (14.0)0.066
    4525 (19.4)11 (30.6)14 (15.1)0.046
    5124 (18.6)13 (36.1)11 (11.8)0.001
    52‡10 (7.8)5 (13.9)5 (5.4)0.106
    5618 (14.0)9 (25.0)9 (9.7)0.025
    5818 (14.0)4 (11.1)14 (15.1)0.557
    5924 (18.6)9 (25.0)15 (16.1)0.244
    6815 (11.6)8 (22.2)7 (7.5)0.019
  • *p Value for difference in prevalence between HIV-positive and HIV-negative men.

  • †Low and high-risk HPV genotypes based on studies of HPV genotypes detected in cervical cancer.15

  • ‡Type 52 HPV result is obtained from a combination probe strip including HPV genotypes 52, 33, 35 and 58. It is recorded as positive if the combination probe is positive, but the independent probes for genotypes 33, 35 and 58 are negative.