Author | Year | ELISA | T pallidum antibodies | Samples total/positive | Sensitivity (%) | Specificity (%) | Remarks |
Ebel et al21 | 1998 | Bioelisa Syphilis | IgG | 824/434 | 99.5 | 99.4 | Positives are TPHA and FTA-Abs positive |
GutiƩrrez et al22 | 2000 | Enzygnost Syphilis | IgG/IgM | 821/401 | 100 | 99.5 | 13 Positive samples were only RPR positive, remainder are MHA-TP positive |
Sambri et al23 | 2001 | RecomWell Treponema | IgG | 122/122 | 98.2 | Positives are MHA-TP positive | |
Castro et al24 | 2003 | ETI-Syphilis-G | IgG | 441/313 | 100 | 93 | Positives are MHA-TP positive |
Aktas et al25 | 2005 | Syphilis ICE | IgG/IgM | 124/100 | 100 | Positives are TPHA positive | |
Enzywell T pallidum | IgG/IgM | 124/100 | 100 | ||||
Viriyataveekul et al26 | 2006 | Enzygnost Syphilis | IgG/IgM | 3055/102 | 100 | 97.9 | Positives are positive in two out of three ELISA and TPHA and/or FTA-Abs |
Syphilis EIA 480 | 3055/102 | 100 | 99.6 | ||||
ICE* Syphilis | 3055/102 | 99.1 | 99.8 |
FTA-Abs, fluorescent treponemal antibody absorption; MHA-TP, microhaemagglutination assay for T pallidum; RPR, rapid plasma reagin test; TPHA, T pallidum haemagglutinin agglutination test.
*ICE is a trademark of Abbott Murex.