Table 1 Overview of different ELISA evaluated for detecting T pallidum antibodies in serum
AuthorYearELISAT pallidum antibodiesSamples total/positiveSensitivity (%)Specificity (%)Remarks
Ebel et al211998Bioelisa SyphilisIgG824/43499.599.4Positives are TPHA and FTA-Abs positive
GutiƩrrez et al222000Enzygnost SyphilisIgG/IgM821/40110099.513 Positive samples were only RPR positive, remainder are MHA-TP positive
Sambri et al232001RecomWell TreponemaIgG122/12298.2Positives are MHA-TP positive
Castro et al242003ETI-Syphilis-GIgG441/31310093Positives are MHA-TP positive
Aktas et al252005Syphilis ICEIgG/IgM124/100100Positives are TPHA positive
Enzywell T pallidumIgG/IgM124/100100
Viriyataveekul et al262006Enzygnost SyphilisIgG/IgM3055/10210097.9Positives are positive in two out of three ELISA and TPHA and/or FTA-Abs
Syphilis EIA 4803055/10210099.6
ICE* Syphilis3055/10299.199.8
  • FTA-Abs, fluorescent treponemal antibody absorption; MHA-TP, microhaemagglutination assay for T pallidum; RPR, rapid plasma reagin test; TPHA, T pallidum haemagglutinin agglutination test.

  • *ICE is a trademark of Abbott Murex.