PMNLs/HPF urethra | FVU PMNLs/HPF | Cervix PMNLs/HPF | Total (FVU or cervix) PMNLs/HPF | ||||||
0–4 | 5–9 | ⩾10 | 0–4 | 5–9 | ⩾10 | 0–4 | 5–9 | ⩾10 | |
M genitalium positive (%) | 73 (39) | 50 (27) | 64 (34) | 117 (45) | 72 (28) | 71 (27) | 134 (44) | 84 (28) | 86 (28) |
OR | 2.1 | 1.4 | 1.5 | ||||||
95% CI | 1.5 to 2.9 | 1.1 to 1.9 | 1.1 to 2.0 | ||||||
C trachomatis positive (%) | 177 (28) | 186 (29) | 275 (43) | 187 (29) | 195 (30) | 271 (41) | 216 (30) | 216 (30) | 294 (40) |
OR | 3.6 | 3.4 | 3.2 | ||||||
95% CI | 3.0 to 4.4 | 2.8 to 4.1 | 2.6 to 3.8 | ||||||
M genitalium and C trachomatis negative (%) | 3395 (51) | 1756 (27) | 1452 (22) | 3359 (52) | 1725 (26) | 1441 (22) | 3378 (51) | 1739 (27) | 1457 (22) |
Association was determined by comparing microscopic examination of polymorphic mononuclear leucocytes per high-powered field (PMNLs/HPF) in urethral smears in turn with microorganisms found in the first void urine (FVU) (Mycoplasma genitalium, n = 187; Chlamydia trachomatis, n = 638; no organism, n = 6603); microorganisms found in the cervix (M genitalium, n = 260; C trachomatis, n = 653; no organism, n = 6525) or microorganisms found in either the FVU or cervical swab specimens (M genitalium, n = 304; C trachomatis, n = 726; no organism, n = 6574). Patients positive for both M genitalium and C trachomatis (n = 42) have been excluded from the calculation.