Characteristics of the gravidas with untreated syphilis recruited in Shenzhen from 2002 to 2007
| Variables | No of mothers who delivered normal infants (%) | No of mothers who delivered infants with CS (%) | Statistical values | p Values |
| Current age (mean± SE, years) | 27.73±0.18 (n=525) | 28.00±0.83 (n=29) | t=0.336 | 0.737 |
| Education | ||||
| Secondary school or below | 267 (50.9) | 20 (69.0) | ||
| High school or above | 258 (49.1) | 9 (31.0) | χ2=3.61 | 0.057 |
| History of other STD | ||||
| No | 482 (91.8) | 28 (96.6) | ||
| Yes | 43 (8.2) | 1 (3.4) | Fisher's exact test | 0.720 |
| Extramarital sexual relations | ||||
| No | 259 (49.3) | 13 (44.8) | ||
| Yes | 266 (50.7) | 16 (55.2) | χ2=0.22 | 0.637 |
| No of pregnancies | ||||
| 1 | 85 (16.3) | 4 (13.8) | ||
| 2 | 153 (29.4) | 10 (34.5) | ||
| 3 | 149 (28.7) | 8 (27.6) | ||
| 4 | 84 (16.2) | 5 (17.2) | ||
| ≥5 | 49 (9.4) | 2 (6.9) | χ2=0.57 | 0.967 |
| Missing | 5 (0.9) | |||
| History of APOs | ||||
| No | 432 (82.3) | 24 (82.8) | ||
| Yes | 93 (17.7) | 5 (17.2) | χ2=0.004 | 0.948 |
| Stage of maternal syphilis | ||||
| Early (<2 years) | 43 (8.2) | 9 (31.0) | ||
| Late (≥2 years or unknown) | 479 (91.8) | 20 (69.0) | Fisher's exact test | 0.001 |
| Missing | 3 (0.5) | |||
| Maternal TRUST titre | ||||
| <1:8 | 366 (70.9) | 4 (13.8) | ||
| ≥1:8 | 150 (29.1) | 25 (86.2) | χ2=41.12 | <0.001 |
| Missing | 9 (1.6) | |||
| Gestational week for treatment (mean±SE, week) | 21.63±0.44 (n=525) | 31.52±1.69 (n=29) | t=5.126 | <0.001 |
APOs, adverse pregnancy outcomes; CS, congenital syphilis; STD, sexually transmitted disease; TRUST, toluidine red unheated serum test.