Parameters specifying the effect of male circumcision on the rate of HIV transmission (ranges used in the uncertainty analysis are presented in table S1 in the online technical appendix)
| Parameter description | Value | Source |
| Mean duration of wound healing period | 14 days (95% healed within 6 weeks). | 34 |
| Change in the rate of female-to-male HIV transmission before wound is healed versus before circumcision | Increases 3-fold | 16 |
| Change in rate of HIV male-to-female HIV transmission before wound is healed versus before circumcision | Increases 3.5-fold | 17 |
| Proportion of men who remain sexually active during the wound healing period | 13% | 16 |
| Change in rate of female-to-male HIV transmission after the wound has healed versus before circumcision | Decreases by 65% | 35 |
| Change in rate of male-to-female HIV transmission before 2 years after the operation versus before circumcision | No effect | 17 |
| Change in rate of male-to-female HIV transmission from 2 years after the operation versus before circumcision | We estimated this after performing a meta-analysis of data from the two studies among HIV sero-discordant couples that measured this effect | 18 19 |