Estimated annual burden and cost of STDs in the USA
| Costs | Reported cases 2009 | Estimated annual new cases* | Estimated annual direct (millions)† |
| Chlamydia | 1 244 180 | 2.8 million | $701 |
| Gonorrhoea | 301 174 | 718 000 | $138 |
| HIV‡ | 42 959 | 60 000§ | $8900 |
| Syphilis | 13 997 | 70 000 | $25 |
| Hepatitis B‡ | 4033 | 80 000 | $47 |
| HPV | NA | 6.2 million | $5800 |
| Genital herpes | NA | 1.6 million | $1100 |
| Trichomoniasis | NA | 7.4 million | $198 |
| Total | 1 606 343 | 18.9 million | $17 billion |
↵* US annual estimated new cases (Weinstock et al.1)
↵† Updated to 2010 $US using medical care component of CPI. Total may differ from sum of all diseases due to rounding. Adapted from Chesson et al.3
↵‡ HIV and hepatitis B estimates include costs of sexually acquired cases only.
↵§ Annual new HIV cases, 2008 estimate; all other annual cases are 2004 estimates (Hall HI, Ruiguang S, Rhodes P, et al. Estimation of HIV incidence in the United States. JAMA 2009;300:520–9.).
HPV, human papillomavirus.