Specific interaction | Best fit attributable fraction (95% CI from all fits) |
% of HIV incidence among FSW due to specific interaction with HSV-2 | |
All interactions combined | 35.5 (22.2 to 62.5) |
Increased susceptibility and infectivity of HIV in the presence of asymptomatic HSV-2 shedding alone | 32.4 (20.4 to 59.5) |
Increased susceptibility and infectivity of HIV in the presence of symptomatic HSV-2 recurrences alone* | 3.0 (1.4 to 4.3) |
Increased susceptibility to HIV among HSV-2-infected FSW | 24.6 (11.2 to 46.7) |
Increased infectivity of HIV from co-infected clients* | 10.4 (2.3 to 32.5) |
↵* Includes implicitly the static effect on HIV transmission of the increased herpes simplex virus type 2 (HSV-2) symptomatic recurrence rate among co-infected clients.
FSW, female sex worker.