Sensitivity analysis on the effect of a 20% change in model interaction inputs on the model best-fit attributable fraction of HIV due to HSV-2 among FSW
| Model input parameters (values used for best fit simulation in parentheses, derived from table S1 in the supplementary online appendix) | Relative % change in attributable fraction of HIV incidence among FSW due to HSV-2 from best fit value of 35.54% (absolute value)* | |
| −20% relative change in parameter | +20% relative change in parameter | |
| Cofactor for increased transmission of HIV to person symptomatically shedding HSV-2 (4.5) | −8.10% (32.66%) | +8.10% (38.42%) |
| Cofactor for increased transmission of HIV from co-infected partner symptomatically shedding HSV-2 (2.7) | −3.70% (34.22%) | +3.70% (36.85%) |
| Cofactor for increased transmission of HSV-2 from co-infected partner with high HIV viraemia (0.76) | −1.15% (35.13%) | +1.15% (35.95%) |
| Cofactor for increased symptomatic HSV-2 shedding rate in those with HIV (1.4) | −0.66% (35.30%) | +0.66% (35.77%) |
| Cofactor for increased asymptomatic HSV-2 shedding in those with HIV (2.4) | −0.24% (35.45%) | +0.24% (35.62%) |
| Cofactor for increased transmission of HSV-2 to a person with high HIV viraemia (1.7) | +0.14% (35.59%) | −0.14% (35.49%) |
↵* R2 value over 0.98 in the multilinear regression.
FSW, female sex worker; HSV-2, herpex simplex virus type 2.