Focus HerpeSelect-2 EIA performance compared to HSV-2 western blot among HIV-1-uninfected participants from seven countries in sub-Saharan Africa
| Index value | Overall (N=3290) | Women (N=1077) | Men (N=2213) | East Africa (N=2162) | Southern Africa (N=1128) | |||||
| Sensitivity (%) | Specificity (%) | Sensitivity (%) | Specificity (%) | Sensitivity (%) | Specificity (%) | Sensitivity (%) | Specificity (%) | Sensitivity (%) | Specificity (%) | |
| 0.9 | 98.9 | 76.0 | 99.6 | 69.2 | 98.4 | 77.0 | 99.1 | 71.7 | 98.4 | 83.4 |
| 1.1 | 98.3 | 80.3 | 99.4 | 72.9 | 97.5 | 81.5 | 98.6 | 76.8 | 97.7 | 86.5 |
| 1.3 | 97.7 | 83.6 | 98.9 | 75.9 | 96.8 | 84.8 | 98.1 | 79.7 | 96.8 | 90.4 |
| 1.5 | 96.6 | 85.5 | 98.4 | 76.7 | 95.4 | 86.9 | 96.9 | 81.3 | 96.1 | 93.0 |
| 1.7 | 95.8 | 87.1 | 98.2 | 79.7 | 94.1 | 88.3 | 96.1 | 83.3 | 95.1 | 93.8 |
| 2.0 | 94.4 | 89.9 | 97.9 | 84.2 | 91.9 | 90.7 | 94.8 | 87.0 | 93.4 | 94.9 |
| 2.3 | 92.0 | 91.4 | 95.9 | 87.2 | 89.3 | 92.0 | 92.6 | 88.9 | 90.7 | 95.8 |
| 2.5 | 90.6 | 91.9 | 95.3 | 87.2 | 87.3 | 92.6 | 91.4 | 89.4 | 89.0 | 96.3 |
| 2.7 | 88.9 | 92.6 | 94.7 | 87.2 | 84.9 | 93.4 | 89.8 | 90.3 | 87.2 | 96.6 |
| 3.0 | 86.9 | 93.9 | 93.4 | 88.7 | 82.4 | 94.7 | 87.7 | 92.1 | 85.2 | 97.2 |
| 3.3 | 84.5 | 94.6 | 91.5 | 89.5 | 79.6 | 95.4 | 85.3 | 93.0 | 82.8 | 97.5 |
| 3.5 | 82.9 | 95.1 | 90.5 | 90.2 | 77.6 | 95.9 | 83.4 | 93.7 | 81.9 | 97.8 |
EIA, enzyme immunoassay; HSV, herpes simplex virus.