Table 1

Model parameters and baseline values

Parameter	Symbol	Baseline value	Source
Probability of developing de novo resistance on therapy	r_A, r_B	0.000001	Assumption
Natural recovery rate (1/year)	v	8.67	Best estimate^*

		High risk	Intermediate risk	Low risk
Population size	N_i	2308	23 077	974 615
Proportion of population		0.0023	0.023	0.97
Total annual partnerships	c_i	9.27	1.62	0.056	Equation (6)
Proportion of sexual partnerships
High risk	p_3i	0.931	0.0669	0.002
Intermediate risk	p_2i	0.4926	0.4926	0.0148
Low risk	p_1i	0.33	0.33	0.33
Baseline daily rate of treatment using drug A and/or B	t_Ai, t_Bi, t_ABi
Single-drug treatment	t_Ai	0.003	0.003	0.003

↵* Based on descriptions in available medical literature on duration of NG infections lasting from weeks to months when untreated.11 30