APTHotline n=135 contactable partners | APTPharmacy n=44 contactable partners | Routine PN n=117 contactable partners | Pharmacy versus routine | Hotline versus routine | ||||
n | % (95% CI) | n | % (95% CI) | n | % (95% CI) | p Value | p Value | |
Primary outcome: | ||||||||
Partners engaged with allocated method | 65/135 | 48 (39 to 58) | 15/44 | 34 (22 to 49) | 13/117 | 11 (6 to 19) | 0.001 | <0.001 |
Partners assumed treated by allocated method | 47/135 | 35 (26 to 45) | 15/44 | 34 (22 to 49) | 13/117 | 11 (6 to 19) | 0.001 | <0.001 |
Partners assumed treated by any method | 80/135 | 59 (49 to 69) | 29/44 | 66 (52 to 78) | 42/117 | 36 (26 to 47) | 0.001 | 0.003 |
Method of ascertainment of primary outcome: | ||||||||
Outcome verified by contact with trial PN arm | 61/80 | 76 (64 to 85) | 15/29 | 52 (34 to 69) | 13/42 | 31 (19 to 47) | 0.086 | <0.001 |
Outcome verified by index at follow-up interview* | 19/80 | 24 (15 to 36) | 14/29 | 48 (31 to 66) | 29/42 | 69 (54 to 81) | 0.086 | <0.001 |
Secondary outcomes: | ||||||||
Partner provided sample for STI testing | 29/49 | 59 (45 to 72) | 6/15 | 40 (19 to 66) | 12/13 | 92 (60 to 99) | 0.009 | 0.030 |
Sample tested | 25/49 | 51 (38 to 64) | 5/15 | 33 (14 to 60) | 12/13 | 92 (60 to 99) | 0.004 | 0.010 |
Sample positive | 7/25† | 28 (14 to 49) | 1/5‡ | 20 (3 to 71) | N/A no consent | N/A | N/A | |
Partner attended clinic for HIV/syphilis testing | 2/49 | 4 (0.5 to 14) | 0/15 | 0 (0 to 22) | 12/13§ | 92 (60 to 99) | <0.001 | <0.001 |
↵* Index patient reported outcomes for partners who engaged with other health services and so were managed outside of trial.
↵† Seven partners tested positive for C trachomatis.
↵‡ One partner tested positive for C trachomatis.
↵§ Two partners declined an HIV test but were tested for syphilis.
Samples were tested for the relevant microbiological and virological pathogens according to each clinic's standard testing protocols, which were compliant with current British Association for Sexual Health and HIV National Testing Guidelines.
APT, Accelerated Partner Therapy.