Table 3

Diagnoses by clinicians compared with reference standard*

Infections	True positive diagnoses	Per cent agreement†	Bias p value	κ (± 95% CI)	Interpretation of κ‡	p Value
Bacterial vaginosis	125
Examining clinician	90	75.66	<0.001	0.50±0.06	Good	<0.001
Non-examining clinician§	68	64.55	<0.001	0.32±0.05	Poor	<0.001
Trichomoniasis	37
Examining clinician	28	91.87	0.62	0.72±0.06	Good	<0.001
Non-examining clinician	24	90.86	0.06	0.67±0.07	Good	<0.001
Vulvovaginal candidiasis	27
Examining clinician*	27
Non-examining clinician	14	91.9±3.8	<0.01	0.59±0.09	Good	<0.001

*Reference standards: BV—Gram stain from SOVS, TV—NAAT testing from SOVS and VVC—examining clinician.
†Per cent agreement includes true positives and true negatives.
‡All κ values were significantly different than 0.
§Non-examining clinicians used information from SOVS and patient history to render a diagnosis.
BV, bacterial vaginosis; NAAT, nucleic acid amplification test; SOVS, self-obtained vaginal swabs; TV, Trichomonas vaginalis; VVC, vulvovaginal candidiasis.