Table 1

Characteristics of included studies

Study	Year	Country	Study design	Number of patients	Age	Adult HIV prevalence in study country	2- or 3-drug regimen	Intervention used
Developed countries
Wiebe et al7	2000	Canada	Retrospective cohort study	71	Adults	0.20%	2	None
Loutfy et al15	2008	Canada	Prospective cohort study	347	Adults and children	0.20%	3	None
Wong et al27	2010	Canada	Retrospective data collection	118	Adults	0.20%	Both	None
Lunding et al30	2010	Denmark	Retrospective data collection	32	Adults	0.20%	3	None
Bani-Sadr et al22	2001	France	Retrospective data collection	109	Adults	0.40%	3	None
Lacombe et al31	2005	France	Retrospective chart review	5	Adults	0.40%	Both	None
Rey et al26	2008	France	Retrospective data collection	98	Adults	0.40%	Inadequate data	None
Limb et al28	2002	UK	Retrospective case note review	8	Adults	0.20%	3	None
MacDonald et al20	2010	UK	Retrospective case note audit	24	Adults	0.20%	Inadequate data	None
Masanzu et al21	2010	UK	Retrospective case note review	77	Adults	0.20%	3	None
Babl et al38	2000	USA	Retrospective review	5	Children	0.60%	3	None
Schremmer et al39	2005	USA	Retrospective review	34	Children and adolescents	0.60%	2	None
Linden et al3	2005	USA	Retrospective chart review	85	Adults	0.60%	Both	None
Olshen et al8	2006	USA	Retrospective chart review	86	Adolescents	0.60%	Both	None
Neu et al37	2007	USA	Prospective, non-randomised observational study	33	Children	0.60%	2	None
Griffith et al29	2010	USA	Retrospective chart review	150	Adults	0.60%	3	None
Developing countries
Garcia et al32	2005	Brazil	Prospective cohort study	278	Adults and children	0.45%	Both	None
Diniz et al35	2007	Brazil	Retrospective data collection	54	Adults and children	0.45%	Inadequate data	None
Speight et al4	2005	Kenya	Retrospective data collection	58	Children	6.30%	2	None
Carries et al25	2007	South Africa	Record review	198	Adults	17.80%	2	None
Collings et al36	2008	South Africa	Prospective cohort study	113	Children	17.80%	2	None
Kim et al33	2009	South Africa	Prospective cohort study	109	Adults and children	17.80%	Inadequate data	Nurse-driven model
Abrahams et al34	2010	South Africa	Randomised controlled trial	274	Adults and children	17.80%	2	Telephonic support
Roland et al24	2011	South Africa	Prospective data collection	131	Adults	17.80%	2	Nurse-driven model