Number of Neisseria gonorrhoeae isolates tested for 7 antimicrobials and the antimicrobial susceptibility profile in 18 participating laboratories
| Country and centre name | Penicillin | Tetracycline | Ciprofloxacin | Ceft | Sp | Az | Cefp | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PPNG | CMR | LS | TRNG | NTRNG | R | LS | R | LS | DS | R | R | DS | |
| Bhutan | |||||||||||||
| JDW/NRH, Thimpu | 376/423* | 393/791 | 22/791 | 150/431† | 281/431 | 293/294 | 1/294 | 749/791 | 15/791 | 7/791 | 5/791 | 0/142‡ | 7/431§ |
| CRRH, Gelephu | ND | 81/82 | 0/82 | ND | ND | 79/82 | 2/82 | 80/82 | 2/82 | 0/82 | 1/82 | ND | ND |
| ERRH, Mongar | ND | 38/38 | 0/38 | ND | ND | 38/38 | 0/38 | 38/38 | 0/38 | 0/38 | 0/38 | ND | ND |
| GH, Phuentsholing | ND | 80/80 | 0/80 | ND | ND | 80/80 | 0/80 | 80/80 | 0/80 | 0/80 | 0/80 | ND | ND |
| Indonesia | ND | ND | ND | ND | ND | 24/24 | 0/24 | 16/16 | 0/16 | 5/16¶ | ND | ND | ND |
| India | |||||||||||||
| AIIMS, Delhi | 40/79 | 8/79 | 31/79 | 24/79 | 55/79 | 24/79 | 24/79 | 74/79 | 3/79 | 6/79 | 0/79 | 3/79 | 6/79 |
| Pune, NARI | 0/4 | 1/4 | 3/4 | ND | ND | 1/4 | 3/4 | 4/4 | 0/4 | 0/4 | 0/4 | ND | ND |
| UCMS and GTB, Delhi | 18/92 | 25/92 | 49/92 | 9/92 | 83/92 | ND | ND | 35/92 | 56/92 | 1/92 | 0/92 | 0/2 | ND |
| RSCs | |||||||||||||
| Chennai | 2/4* | 16/20 | 0/20 | 2/4† | 2/4 | 0/3 | 0/3 | 11/21 | 1/21 | 2/21 | 0/2 | 0/16 | 0/2 |
| Delhi, MAMC | 15/17 | 2/17 | 0/17 | ND | ND | 11/17 | 5/17 | 12/17 | 4/17 | 0/17 | 0/17 | 0/14 | 0/17 |
| Delhi, SJH-RRL | 92/171 | 15/171 | 54/171 | 53/171 | 118/171 | 17/171 | 52/171 | 166/171 | 5/171 | 10/171 | 0/171 | 4/171 | 10/171 |
| Hyderabad | 13/31 | 5/31 | 8/31 | 4/31 | 27/31 | ND | ND | 11/31 | 12/31 | 0/31 | 0/31 | 0/13 | 0/14 |
| Kolkata | 10/19 | 5/19 | 4/19 | 3/8 | 5/8 | ND | ND | 13/19 | 1/19 | 16/19¶ | 2/19** | 0/3 | 11/19†† |
| Nagpur | 0/5 | 3/5 | 2/5 | 0/5 | 5/5 | ND | ND | 4/5 | 1/5 | 0/5 | 0/5 | 0/3 | 2/5†† |
| Vadodra | ND | 1/2 | 0/2 | 0/2 | 2/2 | ND | ND | 0/2 | 0/2 | 0/1 | 0/2 | 1/2 | ND |
| Myanmar | 14/40 | 13/40 | 0/40 | 27/40 | 13/40 | ND | ND | 34/40 | 2/40 | 5/40 | 0/40 | ND | ND |
| Sri Lanka | 126/198 | 30/198 | 21/198 | 38/233 | 195/233 | ND | ND | 213/233 | 0/233 | 0/233 | 0/233 | ND | ND |
| Thailand | 2238/2663* | 8/545 | 69/545 | 120/534 | 414/534 | 318/534 | 53/534 | 2241/2780 | 462/2780 | 1/2936 | 0/2898 | 10/2893 | ND |
*β Lactamase testing in JDW/NRH Bhutan and Chennai started in 2011 and 2012, respectively; in Thailand, testing for penicillin started only in 2012 and 545 isolates were tested.
†TRNG testing by CDS started in Bhutan in 2011. In Chennai, seven isolates were tested for tetracycline: three in 2011 by CLSI and four by CDS in 2012.
‡Azithro testing by CDS started in 2012.
§CPD testing started in 2011. However, the same isolates were having DS to ceftriaxone and cefpodoxime in 2011–2012.
¶Indonesia did not participate in EQAS and isolates having decreased susceptibility to ceftriaxone were not confirmed by RRL. This centre was trained for GASP techniques in 2012 and will join the EQAS network in 2013. Indonesia tested for some other antibiotics also (cefuroxime, Kanamycin, Ofloxacin). Results for these antibiotics are not included in the present study. RRL did not receive 16 isolates from Kolkata having decresed susceptibility to ceftriaxone.
**Results not validated by RRL.
††Results not validated by RRL.
Az, azithromycin; CDS, calibrated dichotomous sensitivity; Cefp, cefpodoxime; Ceft, ceftriaxone; CLSI, Clinical and Laboratory Standards Institute; CMR, chromosomally mediated resistance; CRRH, central regional referral hospital; DS, decreased susceptibility; eqas, external quality assurance scheme; GASP, Gonococcal Antimicrobial Surveillance Program; gh, General Hospital; JDW/NRH, Jigme Dorji Wangchuk National Referral Hospital; LS, less susceptible; MAMC, Maulana Azad Medical College; NARI, National AIDS Research Institute; NTRNG, not TRNG; PPNG, penicillinase producing Neisseria gonorrhoeae; R, resistant; RRL, regional reference laboratory; SJH Safdarjung Hospital; Sp, spectinomycin; TRNG, tetracycline resistant N gonorrhoeae; UCMS and GTB, University College of Medical Sciences and Guru Tegh Bahadur Hospital.